- Currier Museum of Art
Features European and American paintings, decorative arts, photographs, sculpture, and Frank Lloyd Wright's Zimmerman House.
- Christa McAuliffe Planetarium
- Children's Museum of Portsmouth
Features hands-on exhibits about the arts and sciences.
- Clark's Trading Post
Offers family entertainment and museums filled with Americana, steam locomotives, covered bridges, and more.
- Saint-Gaudens National Historic Site
Showcasing the home, gardens, and studios of sculptor Augustus Saint-Gaudens.
- American Independence Museum
- New England Ski Museum
Collects and exhibits elements of ski history for the purpose of research, education, and entertainment.
- U.S. Marconi Museum of Radio Communications
From the U.S. branch of the Guglielmo Marconi Foundation.
- Alma Gilbert, Inc.
Offers works by American artist Maxfield Parrish (1870-1966). Also includes information about the Cornish Colony Gallery and Museum in Cornish, NH.